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Hematocrit (HCT) and packed cell volume (PCV) are used to measure red blood cell mass. An increase in red blood cell mass is equivalent to erythrocytosis and a decrease indicates an anemia. Because HCT and PCV are affected by changes in water the HCT and PCV may be high due to water losses in a dehydrated animal (depending on the extent of dehydration). This can normalize a HCT/PCV in an anemic animal or may increase the HCT/PCV above the upper reference limit in a non-anemic animal resulting in a relative erythrocytosis.
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