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The test looks for antibodies to the EBV Viral Capsid Antigen (VCA). Mononucleosis is brought on by the EBV and is characterised by fatigue fever sore throat swollen lymph nodes and an enlarged spleen. Patients saliva contains the virus which is highly contagious. Only four to six weeks after infection are anti-VCA IgM antibodies detected. An immunocompromised person who has been in close touch with an infected person may also be prescribed the test even in the absence of symptoms.
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