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This test can help identify a thiopurine methyltransferase (TPMT) deficiency and assess your vulnerability to experiencing serious adverse events if you take an immune-suppressing thiopurine medication such azathioprine, mercaptopurine, or thioguanine. There is no specific test preparation required for the genetic test (TPMT genotyping), but the test must be conducted before taking a thiopurine medication since it may impact results when assessing TPMT enzyme activity (TPMT phenotyping).
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