A persons blood can be tested to see if it contains one or more autoantibodies using an extractable nuclear antigen (ENA) qualitative profile. By reacting with proteins that are present in the cell nucleus these autoantibodies cause autoimmune disorders. In order to diagnose autoimmune conditions including polymyositis/dermatomyositis mixed connective tissue disease (MCTD) lupus (SLE) Sgren syndrome and scleroderma a test is used. The test assists in monitoring the illness progression as well. Although autoimmune illnesses can manifest in a variety of ways the most common ones are fever tiredness muscle pains joint swelling hair loss hemolytic anaemia etc