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The quadruple marker test is a comprehensive approach to detect pregnancy at high risk of genetic disorders in foetus. This includes the following screening tests i.e., HCG-β, AFP, uE3, Inhibin A and a reflex test which could be NIPS or Karyotyping reflex to FISH for high-risk cases. This test is recommended for pregnant women at 14 to 22.6 weeks of gestation.
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